McDonald is chasing a second win in the Lightning Stakes having teamed with Waller to win with Home Affairs in 2022.
Like Home Affairs, Switzerland is a three-year-old and is attempting to win the Lightning first-up having won the Group 1 Coolmore Stud Stakes (1200m) at Flemington in the spring.
McDonald said he was looking forward to reuniting with Switzerland on Saturday.
"He is a really good colt. He won the Coolmore in exceptional fashion," McDonald said.
"He ticked that box of up the straight, he excelled up the straight so we're hoping he can do it again against older horses.
"This is a huge test for him, but he's had the perfect preparation in terms of two trials, he had a nice little stretch of the legs up the straight the other day." - James McDonald
"Even though this is probably his toughest test to date he has been well prepared, so we expect him to run really, really well."
Apart from a couple of 'blips' on the radar of Switzerland after winning his first three starts, the colt rebounded strongly in the spring to show the class McDonald has seen in the three-year-old.
"He is a very good horse, he has shown it from day dot, so we're looking forward to seeing if he can make this next serious step to weight-for-age, which I think he can," McDonald said.
"I'm quietly confident he can anyway."